Biological Activities of Stilbenoids

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Biological Activities of Stilbenoids

Stilbenoids are a group of naturally occurring phenolic compounds found in various plant species. They share a common backbone structure known as stilbene, but differ in the nature and position of substituents. Stilbenoids are classified as phytoalexins, which are antimicrobial compounds produced de novo in plants to protect against fungal infection and toxins. In this review, the biological ef...

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Antioxidant Activities of Stilbenoids from Rheum emodi Wall

Rheum emodi Wall has been reported to possess protective effect in many inflammatory diseases and oxidative stress-related injuries. This study aims to investigate antioxidant power of stilbenoids from R. emodi and then explore the material basis for its antioxidant potential. The most abundant stilbenoid piceatannol-4'-O-β-D-glucopyranoside (PICG) and its aglycon piceatannol (PICE) were isolat...

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Stilbenoids from Stemona japonica.

Three new dihydrostilbenes, stilbostemins J-L (1-3), and a new dihydrophenanthrene, stemanthrene F (4), were isolated from the roots of Stemona japonica together with two known bibenzyls, 3,5-dihydroxy-4-methylbibenzyl (5) and 3,5-dihydroxy-2'-methoxy-4-methylbibenzyl (6). Their structures were elucidated by spectroscopic analyses. Compounds 3-6 exhibited strong antibacterial activities against...

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Stilbenoids from Stemona sessilifolia.

Two new dihydrostilbenes, stilbostemins H (1), I (2), and a new dihydrophenanthrene, stemanthrene E (3), were isolated and identified from the roots of Stemona sessilifolia, together with known stilbostemins B, D and G, and stemanthrenes A and C (4-8). Structures of new stilbenoids were established by 1D and 2D (1)H NMR and (13)C NMR spectroscopic analyses.

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Biological activities of leupeptins.

Leupeptins, leupeptin Pr and leupeptin Ac, strongly inhibit proteolysis by plasmin, trypsin and papain, but do not inhibit proteolysis by <#-chymotrypsin. The inhibition is competitive with substrates. The inhibitory effect on esterolysis by plasmin and trypsin is weaker than on proteolysis. The results with derivatives of leupeptins which contain carboxyl or alcohol instead of aldehyde and of ...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2018

ISSN: 1422-0067

DOI: 10.3390/ijms19030792